Sorafenat 200mg (Sorafenib)
Sorafenib is used in the treatment of liver cancer (hepatocellular carcinoma), advanced stage kidney cancer (advanced renal cell carcinoma) and thyroid cancer (differentiated thyroid carcinoma) when standard therapy has failed or is considered unsuitable.
How it works
Sorafenib belongs to the class of drugs called multikinase inhibitors. It slows down the rate of growth of cancer cells by blocking the action of an abnormal protein that signals cancer cells to multiply. It cuts down the blood supply to the cancer cells and stops their growth and proliferation.
Common side effects
nausea; loss of appetite ; constipation; indigestion ; difficulty swallowing ; distortion of the sense of taste ; heartburn ; altered voice ; Fatigue, Diarrhea, pain ; flushed or painful palms or soles ; itching or rash; bleeding ; joint pain ; fever; weight loss; dry skin.
When should you avoid the drug?
Do not use this drug if:
You are allergic to any of the ingredient of the drug including the active ingredient Sorafenib
You are pregnant or breastfeeding because the efficacy of the drug on the new born baby is yet to be determined
Have heart disease
High blood pressure
Have any kind of allergies
Have breathing or any lung problems
If you are on prescribed blood thinners etc.
What are the strengths available?
This drug Sorafenib is available on our website in the following strengths and brand name:
Sorafenat 200 mg
We provide the drug in various pack sizes on our online website.
Who is the manufacturer?
The drugs are manufactured by Natco Pharma, India
How to take it?
Usually 400 mg twice a day is prescribed for an adult, but always take the drug on doctor’s recommendation . This medicine should be taken on empty stomach, one or two hours before any meal. Do not break the tablet, crush or chew it. Swallow the tablet as whole. Keep checking your blood pressure at regular intervals while on the drug dose.
When to take?
The tablet is usually taken two times a day. Take the exact dose, do not increase or decrease the dose without any recommendation from the doctor. Take the tablet at the same time each day, doing this will help you avoid any misdose. Taking the tablet each day should become your habit until the time prescribed by your doctor.
For how long should it be taken?
Take the drug for the time duration prescribed by your doctor. Discontinuing the drug before the complete dose may decrease the benefits of the drug. Only those patients who have experienced the benefits of other drugs of lung cancer treatment to live longer are advised Sorafenib by a professionally experienced doctor.
What if you take too much (overdose)?
You may require urgent medical help in case you take an overdose of the drug. In such a case visit the nearest healthcare center or call your doctor immediately.
What if you miss the dose?
Take the missed dose as soon as you remember, but if its already the time for the next dose then skip the missed dose and take the next dose on the correct time.
Inform the doctor if you are suffering from high blood pressure, bleeding problems, chest pain, heart problems (prolongation of QT interval), kidney problems other than kidney cancer, or liver disease; if you are going to have a surgery or have been recently operated upon.
Seek immediate medical attention if you experience chest pain, severe dizziness, fainting, sweating or shortness of breath, blood in your urine or stools, abnormal vaginal bleeding, severe stomach pain, coughing up blood, or any bleeding that will not stop while receiving treatment with Sorafenib.
Tell your doctor if you are or planning to become pregnant or are breastfeeding, sorafenib may decrease fertility in men and women.
You may need frequent monitoring of fluid balance and electrolytes if you are at risk of renal dysfunction; monitoring of blood calcium levels and thyroid hormones if you are suffering from thyroid cancer.
Frequently asked questions
Q. Is sorafenib safe during pregnancy?
Sorafenib may harm the baby. The drug should only be given if the benefit to the mother is more than the risk to the baby.
Q. Is sorafenib safe during breastfeeding?
Sorafenib is not safe during breastfeeding. It should only be used if no other alternative drug is available. Please follow your doctor's advice regarding its use.
Q. Is sorafenib effective in chemotherapy?
Sorafenib is effective in chemotherapy of liver, kidney and thyroid cancer.
Q. Is sorafenib cytotoxic?
Sorafenib is a cytotoxic agent.
Q. How is sorafenib taken/administered?
Sorafenib is administered orally in the form of two tablets of 200 mg twice a day (total daily dose of 800 mg) on empty stomach at least 1 hour before or 2 hours after eating.
Q. What does sorafenib target?
Sorafenib targets the cancer cells to stop their growth and proliferation.
|Manufacturer||Natco Pharma, India|